TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Guangdong Pharmaceutical University
Curated by ChEMBL
Guangdong Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 1.10nMAssay Description:Inhibition of SGLT2 (unknown origin)More data for this Ligand-Target Pair
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Guangdong Pharmaceutical University
Curated by ChEMBL
Guangdong Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 1.40nMAssay Description:Inhibition of human SGLT2 expressed in HEK293 cells assessed as decrease in [14C]-AMG uptake preincubated for 10 mins followed by [14C]-AMG addition ...More data for this Ligand-Target Pair
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Guangdong Pharmaceutical University
Curated by ChEMBL
Guangdong Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 2.20nMAssay Description:Inhibition of SGLT2 (unknown origin)More data for this Ligand-Target Pair
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Guangdong Pharmaceutical University
Curated by ChEMBL
Guangdong Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 2.30nMAssay Description:Inhibition of SGLT2 (unknown origin)More data for this Ligand-Target Pair
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Guangdong Pharmaceutical University
Curated by ChEMBL
Guangdong Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 3.10nMAssay Description:Inhibition of SGLT2 (unknown origin)More data for this Ligand-Target Pair
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Guangdong Pharmaceutical University
Curated by ChEMBL
Guangdong Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of SGLT2 (unknown origin)More data for this Ligand-Target Pair
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Guangdong Pharmaceutical University
Curated by ChEMBL
Guangdong Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 8.40nMAssay Description:Inhibition of SGLT2 (unknown origin)More data for this Ligand-Target Pair
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Guangdong Pharmaceutical University
Curated by ChEMBL
Guangdong Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 126nMAssay Description:Inhibition of human SGLT2 expressed in HEK293 cells assessed as decrease in [14C]-AMG uptake preincubated for 10 mins followed by [14C]-AMG addition ...More data for this Ligand-Target Pair
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Guangdong Pharmaceutical University
Curated by ChEMBL
Guangdong Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 170nMAssay Description:Inhibition of human recombinant His-tagged c-MET kinase using 5FAM-KKKSPGEYVNIGFG-NH2 as substrate after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Guangdong Pharmaceutical University
Curated by ChEMBL
Guangdong Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 184nMAssay Description:Inhibition of human SGLT2 expressed in HEK293 cells assessed as decrease in [14C]-AMG uptake preincubated for 10 mins followed by [14C]-AMG addition ...More data for this Ligand-Target Pair
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Guangdong Pharmaceutical University
Curated by ChEMBL
Guangdong Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 246nMAssay Description:Inhibition of human SGLT2 expressed in HEK293 cells assessed as decrease in [14C]-AMG uptake preincubated for 10 mins followed by [14C]-AMG addition ...More data for this Ligand-Target Pair
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Guangdong Pharmaceutical University
Curated by ChEMBL
Guangdong Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 290nMAssay Description:Inhibition of human recombinant His-tagged c-MET kinase using 5FAM-KKKSPGEYVNIGFG-NH2 as substrate after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Guangdong Pharmaceutical University
Curated by ChEMBL
Guangdong Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 380nMAssay Description:Inhibition of human recombinant His-tagged c-MET kinase using 5FAM-KKKSPGEYVNIGFG-NH2 as substrate after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Guangdong Pharmaceutical University
Curated by ChEMBL
Guangdong Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 420nMAssay Description:Inhibition of human recombinant His-tagged c-MET kinase using 5FAM-KKKSPGEYVNIGFG-NH2 as substrate after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Guangdong Pharmaceutical University
Curated by ChEMBL
Guangdong Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 450nMAssay Description:Inhibition of human recombinant His-tagged c-MET kinase using 5FAM-KKKSPGEYVNIGFG-NH2 as substrate after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Guangdong Pharmaceutical University
Curated by ChEMBL
Guangdong Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 580nMAssay Description:Inhibition of human recombinant His-tagged c-MET kinase using 5FAM-KKKSPGEYVNIGFG-NH2 as substrate after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Guangdong Pharmaceutical University
Curated by ChEMBL
Guangdong Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 640nMAssay Description:Inhibition of human recombinant His-tagged c-MET kinase using 5FAM-KKKSPGEYVNIGFG-NH2 as substrate after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Guangdong Pharmaceutical University
Curated by ChEMBL
Guangdong Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 830nMAssay Description:Inhibition of human recombinant His-tagged c-MET kinase using 5FAM-KKKSPGEYVNIGFG-NH2 as substrate after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
Guangdong Pharmaceutical University
Curated by ChEMBL
Guangdong Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 1.83E+3nMAssay Description:Inhibition of human SGLT1 expressed in HEK293 cells assessed as decrease in [14C]-AMG uptake preincubated for 10 mins followed by [14C]-AMG addition ...More data for this Ligand-Target Pair
TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
Guangdong Pharmaceutical University
Curated by ChEMBL
Guangdong Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human SGLT1 expressed in HEK293 cells assessed as decrease in [14C]-AMG uptake preincubated for 10 mins followed by [14C]-AMG addition ...More data for this Ligand-Target Pair
TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
Guangdong Pharmaceutical University
Curated by ChEMBL
Guangdong Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human SGLT1 expressed in HEK293 cells assessed as decrease in [14C]-AMG uptake preincubated for 10 mins followed by [14C]-AMG addition ...More data for this Ligand-Target Pair
TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
Guangdong Pharmaceutical University
Curated by ChEMBL
Guangdong Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human SGLT1 expressed in HEK293 cells assessed as decrease in [14C]-AMG uptake preincubated for 10 mins followed by [14C]-AMG addition ...More data for this Ligand-Target Pair
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Guangdong Pharmaceutical University
Curated by ChEMBL
Guangdong Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of human recombinant His-tagged c-MET kinase using 5FAM-KKKSPGEYVNIGFG-NH2 as substrate after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Guangdong Pharmaceutical University
Curated by ChEMBL
Guangdong Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 3.70E+4nMAssay Description:Inhibition of human recombinant His-tagged c-MET kinase using 5FAM-KKKSPGEYVNIGFG-NH2 as substrate after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Guangdong Pharmaceutical University
Curated by ChEMBL
Guangdong Pharmaceutical University
Curated by ChEMBL
Affinity DataEC50: 54nMAssay Description:Agonist activity at human FFA1 expressed in CHO cells assessed as increase in intracellular Ca2+ flux by Fluo-4 dye based FLIPR assayMore data for this Ligand-Target Pair
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Guangdong Pharmaceutical University
Curated by ChEMBL
Guangdong Pharmaceutical University
Curated by ChEMBL
Affinity DataEC50: 19nMAssay Description:Agonist activity at human FFA1 expressed in CHO cells assessed as increase in intracellular Ca2+ flux by Fluo-4 dye based FLIPR assayMore data for this Ligand-Target Pair
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Guangdong Pharmaceutical University
Curated by ChEMBL
Guangdong Pharmaceutical University
Curated by ChEMBL
Affinity DataEC50: 38nMAssay Description:Agonist activity at human FFA1 expressed in CHO cells assessed as increase in intracellular Ca2+ flux by Fluo-4 dye based FLIPR assayMore data for this Ligand-Target Pair
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Guangdong Pharmaceutical University
Curated by ChEMBL
Guangdong Pharmaceutical University
Curated by ChEMBL
Affinity DataEC50: 157nMAssay Description:Agonist activity at human FFA1 expressed in CHO cells assessed as increase in intracellular Ca2+ flux by Fluo-4 dye based FLIPR assayMore data for this Ligand-Target Pair
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Guangdong Pharmaceutical University
Curated by ChEMBL
Guangdong Pharmaceutical University
Curated by ChEMBL
Affinity DataEC50: 104nMAssay Description:Agonist activity at human FFA1 expressed in CHO cells assessed as increase in intracellular Ca2+ flux by Fluo-4 dye based FLIPR assayMore data for this Ligand-Target Pair
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Guangdong Pharmaceutical University
Curated by ChEMBL
Guangdong Pharmaceutical University
Curated by ChEMBL
Affinity DataEC50: 46nMAssay Description:Agonist activity at human FFA1 expressed in CHO cells assessed as increase in intracellular Ca2+ flux by Fluo-4 dye based FLIPR assayMore data for this Ligand-Target Pair
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Guangdong Pharmaceutical University
Curated by ChEMBL
Guangdong Pharmaceutical University
Curated by ChEMBL
Affinity DataEC50: 40nMAssay Description:Agonist activity at human FFA1 expressed in CHO cells assessed as increase in intracellular Ca2+ flux by Fluo-4 dye based FLIPR assayMore data for this Ligand-Target Pair
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Guangdong Pharmaceutical University
Curated by ChEMBL
Guangdong Pharmaceutical University
Curated by ChEMBL
Affinity DataEC50: 7.90nMAssay Description:Agonist activity at human FFA1 expressed in CHO cells assessed as increase in intracellular Ca2+ flux by Fluo-4 dye based FLIPR assayMore data for this Ligand-Target Pair
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Guangdong Pharmaceutical University
Curated by ChEMBL
Guangdong Pharmaceutical University
Curated by ChEMBL
Affinity DataEC50: 54nMAssay Description:Agonist activity at human FFA1 expressed in CHO cells assessed as increase in intracellular Ca2+ flux by Fluo-4 dye based FLIPR assayMore data for this Ligand-Target Pair
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Guangdong Pharmaceutical University
Curated by ChEMBL
Guangdong Pharmaceutical University
Curated by ChEMBL
Affinity DataEC50: 32nMAssay Description:Agonist activity at human FFA1 expressed in CHO cells assessed as increase in intracellular Ca2+ flux by Fluo-4 dye based FLIPR assayMore data for this Ligand-Target Pair
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Guangdong Pharmaceutical University
Curated by ChEMBL
Guangdong Pharmaceutical University
Curated by ChEMBL
Affinity DataEC50: 28nMAssay Description:Agonist activity at human FFA1 expressed in CHO cells assessed as increase in intracellular Ca2+ flux by Fluo-4 dye based FLIPR assayMore data for this Ligand-Target Pair
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Guangdong Pharmaceutical University
Curated by ChEMBL
Guangdong Pharmaceutical University
Curated by ChEMBL
Affinity DataEC50: 1.86E+4nMAssay Description:Agonist activity at human FFAR1 expressed in CHO cells assessed as increase in intracellular calcium level by Fluo 4-AM dye-based FLIPR assayMore data for this Ligand-Target Pair
TargetFree fatty acid receptor 4(Homo sapiens (Human))
Guangdong Pharmaceutical University
Curated by ChEMBL
Guangdong Pharmaceutical University
Curated by ChEMBL
Affinity DataEC50: 396nMAssay Description:Agonist activity at human FFAR4 expressed in CHO cells assessed as beta-arrestin recruitment after 90 mins by luminescence assayMore data for this Ligand-Target Pair
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Guangdong Pharmaceutical University
Curated by ChEMBL
Guangdong Pharmaceutical University
Curated by ChEMBL
Affinity DataEC50: 1.05E+4nMAssay Description:Agonist activity at human FFAR1 expressed in CHO cells assessed as increase in intracellular calcium level by Fluo 4-AM dye-based FLIPR assayMore data for this Ligand-Target Pair
TargetFree fatty acid receptor 4(Homo sapiens (Human))
Guangdong Pharmaceutical University
Curated by ChEMBL
Guangdong Pharmaceutical University
Curated by ChEMBL
Affinity DataEC50: 63nMAssay Description:Agonist activity at human FFAR4 expressed in CHO cells assessed as beta-arrestin recruitment after 90 mins by luminescence assayMore data for this Ligand-Target Pair
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Guangdong Pharmaceutical University
Curated by ChEMBL
Guangdong Pharmaceutical University
Curated by ChEMBL
Affinity DataEC50: 7.90E+3nMAssay Description:Agonist activity at human FFAR1 expressed in CHO cells assessed as increase in intracellular calcium level by Fluo 4-AM dye-based FLIPR assayMore data for this Ligand-Target Pair
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Guangdong Pharmaceutical University
Curated by ChEMBL
Guangdong Pharmaceutical University
Curated by ChEMBL
Affinity DataEC50: 7.59E+4nMAssay Description:Agonist activity at human FFAR1 expressed in CHO cells assessed as increase in intracellular calcium level by Fluo 4-AM dye-based FLIPR assayMore data for this Ligand-Target Pair
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Guangdong Pharmaceutical University
Curated by ChEMBL
Guangdong Pharmaceutical University
Curated by ChEMBL
Affinity DataEC50: 5.26E+4nMAssay Description:Agonist activity at human FFAR1 expressed in CHO cells assessed as increase in intracellular calcium level by Fluo 4-AM dye-based FLIPR assayMore data for this Ligand-Target Pair
TargetFree fatty acid receptor 4(Homo sapiens (Human))
Guangdong Pharmaceutical University
Curated by ChEMBL
Guangdong Pharmaceutical University
Curated by ChEMBL
Affinity DataEC50: 127nMAssay Description:Agonist activity at human FFAR4 expressed in CHO cells assessed as beta-arrestin recruitment after 90 mins by luminescence assayMore data for this Ligand-Target Pair
TargetFree fatty acid receptor 4(Homo sapiens (Human))
Guangdong Pharmaceutical University
Curated by ChEMBL
Guangdong Pharmaceutical University
Curated by ChEMBL
Affinity DataEC50: 196nMAssay Description:Agonist activity at human FFAR4 expressed in CHO cells assessed as beta-arrestin recruitment after 90 mins by luminescence assayMore data for this Ligand-Target Pair
TargetFree fatty acid receptor 4(Homo sapiens (Human))
Guangdong Pharmaceutical University
Curated by ChEMBL
Guangdong Pharmaceutical University
Curated by ChEMBL
Affinity DataEC50: 75nMAssay Description:Agonist activity at human FFAR4 expressed in CHO cells assessed as beta-arrestin recruitment after 90 mins by luminescence assayMore data for this Ligand-Target Pair
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Guangdong Pharmaceutical University
Curated by ChEMBL
Guangdong Pharmaceutical University
Curated by ChEMBL
Affinity DataEC50: 34nMAssay Description:Agonist activity at human FFAR1 expressed in CHO cells assessed as increase in intracellular calcium level by Fluo 4-AM dye-based FLIPR assayMore data for this Ligand-Target Pair
TargetFree fatty acid receptor 4(Homo sapiens (Human))
Guangdong Pharmaceutical University
Curated by ChEMBL
Guangdong Pharmaceutical University
Curated by ChEMBL
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human FFAR4 expressed in CHO cells assessed as beta-arrestin recruitment after 90 mins by luminescence assayMore data for this Ligand-Target Pair
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Guangdong Pharmaceutical University
Curated by ChEMBL
Guangdong Pharmaceutical University
Curated by ChEMBL
Affinity DataEC50: 94nMAssay Description:Agonist activity at human FFA1 receptor expressed in CHO cells assessed as increase in intracellular calcium levels measured for 90 secs by Fluo 4-AM...More data for this Ligand-Target Pair
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Guangdong Pharmaceutical University
Curated by ChEMBL
Guangdong Pharmaceutical University
Curated by ChEMBL
Affinity DataEC50: 76nMAssay Description:Agonist activity at human FFA1 receptor expressed in CHO cells assessed as increase in intracellular calcium levels measured for 90 secs by Fluo 4-AM...More data for this Ligand-Target Pair
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Guangdong Pharmaceutical University
Curated by ChEMBL
Guangdong Pharmaceutical University
Curated by ChEMBL
Affinity DataEC50: 33nMAssay Description:Agonist activity at human FFA1 receptor expressed in CHO cells assessed as increase in intracellular calcium levels measured for 90 secs by Fluo 4-AM...More data for this Ligand-Target Pair